{"id":5242,"date":"2021-05-17T13:25:16","date_gmt":"2021-05-17T17:25:16","guid":{"rendered":"http:\/\/www.380cebbe0d.nxcli.io\/pharmacy\/?p=5242"},"modified":"2021-05-17T13:25:41","modified_gmt":"2021-05-17T17:25:41","slug":"pharm-sci-spring-accomplishments-2-2","status":"publish","type":"post","link":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/news\/pharm-sci-spring-accomplishments-2-2\/","title":{"rendered":"Pharm Sci Summer Accomplishments"},"content":{"rendered":"

[vc_row][vc_column][vc_column_text]There were a lot of accomplishments from March to May in the Department of Pharmaceutical Sciences! The notable list includes:<\/p>\n

\"Christine<\/p>\n

Christine dengler-Crish, Ph.D.<\/u><\/strong><\/h3>\n
grants<\/em><\/strong><\/h6>\n
    \n
  • 1R56AG069116-01A1 NATIONAL INSTITUTE ON AGING 2021. Mechanism of ZCCHC6 Regulation of Mitochondrial Dysfunction In Alzheimer’s Disease. PI: T. Haqqi, Co-I: C. Dengler-Crish<\/strong>, M. Ansari, S. Fleming, Z. Zhu.
    \nAward: $751,425<\/li>\n<\/ul>\n
    peer-reviewed publications<\/em><\/strong><\/h6>\n
      \n
    • Katie A Bretland, Li Lin, Kimberly M Bretland, Matthew A Smith, Sheila M Fleming, Christine M Dengler-Crish<\/strong>. 2021. Irisin treatment lowers levels of phosphorylated tau in the hippocampus of pre-symptomatic female but not male htau mice. Neuropathol Appl Neurobiol, Mar 26. doi: 10.1111\/nan.12711.<\/li>\n<\/ul>\n
      \n

      \"altaf<\/h3>\n

      altaf darvesh, Ph.D.<\/u><\/strong><\/h3>\n
      awards<\/em><\/strong><\/h6>\n
        \n
      • Selected by COP Class of 2021 as a Commencement Hooder<\/li>\n<\/ul>\n
        \n

        \"Sheila<\/p>\n

        Sheila Fleming, Ph.D.<\/u><\/strong><\/h3>\n
        grants<\/em><\/strong><\/h6>\n
          \n
        • 1R56AG069116-01A1 NATIONAL INSTITUTE ON AGING 2021. Mechanism of ZCCHC6 Regulation of Mitochondrial Dysfunction In Alzheimer’s Disease. PI: T. Haqqi, Co-I: C. Dengler-Crish, M. Ansari, S. Fleming<\/strong>, Z. Zhu.
          \nAward: $751,425<\/li>\n<\/ul>\n
          peer-reviewed publications<\/em><\/strong><\/h6>\n
            \n
          • Annand CT, Fleming SM<\/strong>, Holden JG (2021). Farey trees explain sequential effects in choice response time. Frontiers in Physiology, in press.<\/li>\n
          • Katie A Bretland, Li Lin, Kimberly M Bretland, Matthew A Smith, Sheila M Fleming<\/strong>, Christine M Dengler-Crish. 2021. Irisin treatment lowers levels of phosphorylated tau in the hippocampus of pre-symptomatic female but not male htau mice. Neuropathol Appl Neurobiol, Mar 26. doi: 10.1111\/nan.12711.<\/li>\n<\/ul>\n
            abstracts\/posters\/presentations<\/em><\/strong><\/h6>\n
              \n
            • Guest Speaker- Seminar Series, Department of Neurobiology & Behavior, SUNY Stony Brook, NY”ATP13A2: Environmental and genetic interactions in Parkinson’s disease”. (April 1, 2021)<\/li>\n<\/ul>\n
              awards<\/em><\/strong><\/h6>\n
                \n
              • Awarded 2021 College of Pharmacy Excellence in Scholarship Award<\/li>\n<\/ul>\n
                \n

                \"Takhar<\/p>\n

                takhar kasumov, Ph.D.<\/u><\/strong><\/h3>\n
                grants<\/em><\/strong><\/h6>\n
                  \n
                • NIH\/NIDDK (PI: Schelling W., Metro Health) 05\/01-2021-03\/31\/2026
                  \nRole: Co-Investigator
                  \nTitle: Mechanisms of Tubular Atrophy in Renal Disease<\/li>\n
                • North East Ohio Alcohol Center Pilot Grant 06\/01\/2021-04\/31\/2022
                  \nRole: Principal Investigator
                  \nTitle: Temporal changes in hepatic proteome and acetylome in response to alcohol.
                  \nAward: $20,000\/yr<\/li>\n
                • I-CORPS@OH 05\/01\/2021-11\/30\/2021
                  \nRole: Principal Investigator
                  \nTitle: Apomarker – Serum levels of glycated ApoAI, a novel biomarker to screen for pre-diabetes and diabetes and their cardiovascular complications
                  \nAward: $12,500<\/li>\n<\/ul>\n
                  peer-reviewed publications<\/em><\/strong><\/h6>\n
                    \n
                  • Arias-Alvarado A., Aghayev M., Ilchenko S., Rachdaui N., Lepp J., Tsai TH, Zhang G., Previs S., Kasumov T*<\/strong>. Measuring acetyl-CoA and acetylated histone turnover in vivo: Effect of a high fat diet. Analytical Biochemistry<\/em>, 2021, 15, 615: 114067.<\/li>\n
                  • Gabisonia K., Burjanadze G., Woitek F., Keles A., Seki M., Gorgodze N., Carlucci L., Ilchenko S., Kurishima C., Walsh K., Piontkivska H., Recchia F. A., Kasumov T*<\/strong>. Dynamic proteomics and bioinformatics reveal major alterations in the turnover rate of functionally related cardiac and plasma proteins in a dog model of congestive heart failure. Journal of Molecular Cellular Cardiology<\/em>, 2021 (in review<\/em>).<\/li>\n<\/ul>\n
                    abstracts\/posters\/presentations<\/em><\/strong><\/h6>\n
                      \n
                    • Arias-Alvarado A., Ilchenko S., E.Reed, Kashyap, S., Kasumov T<\/strong>. Glycation of the lipoprotein ApoAI is a novel biomarker for early predicting diabetic cardiovascular complications. TechConnect<\/em>, October 18-21, 2021, Washington DC (submitted<\/em>).<\/li>\n<\/ul>\n
                      \n

                      \"headshot<\/p>\n

                      moses oyewumi, Ph.D.<\/u><\/strong><\/h3>\n
                      abstracts\/posters\/presentations<\/em><\/strong><\/h6>\n
                        \n
                      • \u201cAssessment of 3D-Printed Scaffolds as a Platform for Bone Delivery of Gallium Acetyl Acetonate\u201d will be presented at the 2021 Annual meeting of American Association of Pharmaceutical Scientists.<\/li>\n<\/ul>\n
                        \n

                        \"\"<\/p>\n

                        erin reed-geaghan, Ph.D.<\/u><\/strong><\/h3>\n
                        grants<\/em><\/strong><\/h6>\n
                          \n
                        • Awarded $100,000\/year for 3 years from BrightFocus Foundation to support the project \u201cDevelopmental determinants of sexually divergent neuroinflammatory processes in Alzheimer\u2019s disease\u201d.<\/li>\n<\/ul>\n
                          peer-reviewed publications<\/em><\/strong><\/h6>\n
                            \n
                          • Casali BT, Reed-Geaghan EG<\/strong>. (2021) Microglial function and regulation during development, homeostasis and Alzheimer\u2019s disease. Cells<\/em>: in press.<\/li>\n<\/ul>\n
                            abstracts\/posters\/presentations<\/em><\/strong><\/h6>\n
                              \n
                            • The abstract \u201cSex specific dependence on nuclear receptor-mediated myeloid cell activation in Alzheimer\u2019s disease\u201d was accepted for a poster presentation at the 2021 annual Organization for the Study of Sex Differences meeting.<\/li>\n<\/ul>\n
                              awards<\/em><\/strong><\/h6>\n
                                \n
                              • Awarded 2021 College of Pharmacy Innovation in Teaching Award<\/li>\n<\/ul>\n
                                \n

                                \"headshot<\/p>\n

                                austin shin, Ph.D.<\/u><\/strong><\/h3>\n
                                awards<\/em><\/strong><\/h6>\n
                                  \n
                                • Awarded 2021 P1 Teacher of the Year Award<\/li>\n<\/ul>\n
                                  \n

                                  \"Matthew<\/p>\n

                                  matthew smith, Ph.D.<\/u><\/strong><\/h3>\n
                                  peer-reviewed publications<\/em><\/strong><\/h6>\n
                                    \n
                                  • Katie A Bretland, Li Lin, Kimberly M Bretland, Matthew A Smith<\/strong>, Sheila M Fleming, Christine M Dengler-Crish. 2021. Irisin treatment lowers levels of phosphorylated tau in the hippocampus of pre-symptomatic female but not male htau mice. Neuropathol Appl Neurobiol, Mar 26. doi: 10.1111\/nan.12711.<\/li>\n<\/ul>\n
                                    \n

                                    \"headshot<\/p>\n

                                    xinwen wang, Ph.D.<\/u><\/strong><\/h3>\n
                                    peer-reviewed publications<\/em><\/strong><\/h6>\n
                                      \n
                                    • Wang X<\/strong>, Her L, Xiao J, Shi J, Wu A. H., Bleske B. E., and Zhu HJ, Carboxylesterase 1 genetic polymorphism on trandolapril activation in human and the pharmacokinetics and pharmacodynamics in healthy volunteers, Clin Transl Sci<\/em>, 2021<\/li>\n
                                    • Li J, Liu S, Shi J, Wang X<\/strong>, Xue Y, and Zhu HJ, Tissue-Specific Proteomics Analysis of Anti-COVID-19 Nucleoside and Nucleotide Prodrug-Activating Enzymes Provides Insights into the Optimization of Prodrug Design and Pharmacotherapy Strategy, ACS Pharmacol. Transl. Ssi. <\/em>2021, 4 (2): 870-887<\/li>\n<\/ul>\n

                                      [\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"

                                      [vc_row][vc_column][vc_column_text]There were a lot of accomplishments from March to May in the Department of Pharmaceutical Sciences! The notable list includes: Christine dengler-Crish, Ph.D. grants 1R56AG069116-01A1 NATIONAL INSTITUTE ON AGING 2021. […]<\/p>\n","protected":false},"author":102,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[26,28,30],"tags":[],"class_list":["post-5242","post","type-post","status-publish","format-standard","hentry","category-college-update","category-faculty-pride","category-research-pride"],"acf":[],"_links":{"self":[{"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/posts\/5242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/users\/102"}],"replies":[{"embeddable":true,"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/comments?post=5242"}],"version-history":[{"count":4,"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/posts\/5242\/revisions"}],"predecessor-version":[{"id":5246,"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/posts\/5242\/revisions\/5246"}],"wp:attachment":[{"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/media?parent=5242"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/categories?post=5242"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/380cebbe0d.nxcli.io\/pharmacy\/wp-json\/wp\/v2\/tags?post=5242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}